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NF-kappa B activation as a pathological mechanism of septic shock and inflammation
Moreover, 5 mg/kg 3-bromopyruvate (glycolysis inhibitor) in a mouse with arthritis induced by K/BxN mouse serum reduces clinical score, proinflammatory cytokines in the joint, inflammatory cell infiltration, joint destruction, and cartilage damage 27 , which has made it possible to consider glycolysis pathway inhibition as a potential pharmacological target for RA 29
Endocrine (2003) 20:7582
Li Z, Du H, Xie F, et al
Recently discovered GSH-independent compounds, such as FSP1, also modulate tumor ferroptosis (52)
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