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Summary of Policies Discussed in the CY 2025 PFS Final Rule In the CY 2025 PFS proposed rule (89 FR 62245), to fulfill the statutory requirement to remove 340B units from rebate calculations beginning on January 1, 2026, we proposed at 428.203(b)(2)(i) to exclude from the total number of units determined under 428.203(a), units for which a manufacturer provided a discount under the 340B Program (340B units)

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doi: 10.3390/cancers15030855 139 AliyariSRQuanquinNPernetOZhangSWangLChengG

Mice were euthanized at 18 weeks of age for analysis

Some practitioners theorize that IV administration might provide advantages for certain applications, though clinical evidence supporting superiority of IV over IM administration for most wellness purposes remains limited