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B12 is fundamental to a number of important metabolic processes, including: Red blood cell formation Nervous system function Nutrient absorption Adrenal gland support Cognitive function and memory Brain cell regeneration DNA synthesis Mitochondrial metabolism Male and female reproductive health Because of its important role in the nervous system, severe B12 depletion over time can lead to irreversible neurological damage

10.1146/annurev-biochem-030409-143539

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5-Amino-1MQ is also known as 5-amino-1-methylquinolinium (IUPAC-style chemical name), 5amino-1MQ (condensed notation), and NNMT inhibitor (functional class)

Challenges and Future Directions While the preliminary results of 5-Amino-1MQ are promising, its essential to acknowledge that the journey from preclinical studies to human applications is complex