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Disruption of Vesicular Storage (VMAT2): Once inside the neuronal cytosol, amphetamine is taken up into synaptic storage vesicles (predominantly those in a finite readily releasable pool ) via the vesicular monoamine transporter 2 (VMAT2)

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Before nanocarrier cell entry experiments, the non-toxic concentrations of endocytosis and metabolic inhibitors on the cARLA treated hEC were determined by cell viability assays, namely impedance measurement and MTT tests (Fig

Its multi-target mechanisms also indicate therapeutic potential for metabolic, renal, and neurodegenerative disorders

Gould RL, Pazdro R