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Always discuss your complete medical history, current medications, and any concerns with your healthcare provider before starting treatment

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If your prescription says 5 mg weekly and your calculation shows 4 mg or 8 mg, something is wrong

People switch for coverage changes, side-effect profiles, or different effectiveness

As a consequence, SELECT has raised the evidence threshold that innovators must clear when targeting conditions such as hypertension, dyslipidaemia or heart failure, including the effect size they need to demonstrate to be clinically meaningful and patient relevant