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Specifically, it stimulates the activity of three rate-limiting dehydrogenases: pyruvate dehydrogenase (PDH), isocitrate dehydrogenase (IDH), and -ketoglutarate dehydrogenase (-KGDH) (Robb-Gaspers et al., 1998) to the electron transport chain, thereby sustaining oxidative phosphorylation and ATP synthesis (Tarasov et al., 2012)

doi:10.1016/S2213-8587(17)30412-6 Semaglutide Dosage Guide + Max Dose, Adjustments

It's important to note that these side effects are typically mild and often resolve on their own

Cellular and Molecular Mechanisms of Action of Mitochondria-Targeted Antioxidants

However, these are not grounded in definitive evidence