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Speciation studies in CSF demonstrated that exposure of the brain tissue to hexavalent Se may be involved in Alzheimers (Vinceti et al., 2017a, 2019) or amyotrophic lateral sclerosis pathology (Vinceti et al., 2013b

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The most effective dosage, which improved red cell shape and decreased sickling, was 10 mg/ml

Sulfur-rich plasma proteins, including albumin and ceruloplasmin, further buffer redox stress by chelating metal ions and exhibiting thiol-based antioxidant effects (21)

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