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BPC 157 application largely counteracted changes at the microscopic level, including the formation of vacuoles and the loss of axons in the white matter, the formation of edema and the loss of motoneurons in the gray matter, and a decreased number of large myelinated axons in the rat caudal nerve from day 7

These changes in gene expression are dependent on the time interval during which the genes were analyzed, as well as the type of vessel investigated

The committees recommendation is not a binding decision, and the addition of the peptides to the list will still have to go through a lengthy public rulemaking process