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Starting dose (adults): -thalassemia: 1 mg/kg once every 3 weeks

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Palma M, Chaufan M, Breuer CB, Mller S, Sabatier M, Fraser CS, et al

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Ethics declarations Conflict of interest Kohzo Takebayashi, Yurina Iemura, Mototaka Yamauchi, Takafumi Tsuchiya and Shigeki Machida have no conflicts of interest to declare

Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-jun N-terminal kinase-mediated activation of mitochondria-dependent pathway