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Because the data in the TriNetX platform is HIPAA de-identified, and therefore, by definition is deemed to allow no access to protected health information (and therefore no risk of protected health information disclosure), Institutional Review Boards (IRBs) have no jurisdiction of studies using HIPAA de-identified data 53

In addition to dry mouth, these can include: Diarrhea or constipation Abdominal discomfort Gallbladder problems Low blood sugar (hypoglycemia) Pancreatitis Kidney problems That said, semaglutide does not tend to cause significant long-term side effects for most people with diabetes