GLP-1 receptor agonists (GLP-1 RAs), which regulate glucose metabolism through mechanisms such as enhancing glucose-dependent insulin secretion via the incretin effect, suppressing glucagon secretion, delaying gastric emptying, and supporting pancreatic -cell proliferation, are primarily used in the management of type 2 diabetes mellitus (T2DM) and, in certain cases, obesity [23]
While I've experienced other GI-related issues on a GLP-1, nausea has been the most difficult to manage
GLP-1 medications can be especially relevant in these cases because they affect appetite and glucose-related pathways
Some possible drug interactions with Tradjenta include: Amlodipine Aspirin Furosemide (Lasix, Diaqua-2, Lo-Aqua) Glimepiride (Amaryl) Glipizide (Glucotrol, Glucotrol XL, GlipiZIDE XL) Insulin Invokana (canagliflozin) Lantus (insulin glargine) Levothyroxine (Synthroid, Levoxyl, Tirosint, Eltroxin, Levothroid, Levothyrox, Euthyrox, Unithroid, Levo-T, Oroxine, L Thyroxine Roche, Eutroxsig, Novothyrox, Tirosint-Sol, Levotabs, Levotec, Evotrox) Lisinopril (Zestril, Prinivil, Qbrelis) Beta-blockers may also interact with Tradjenta
Each medication has a unique receptor-binding profile that may suit your genetic makeup better