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Our group previously demonstrated that Naotai Formula (NTF) enhances the HSF1/HSPB1 pathway and regulates brain iron homeostasis by suppressing TFR1/dMT1 and activating SCL7A11/GPX4, thereby protecting against ferroptosis in MCAO rats (177, 178)

Diab Vasc Dis Res 14:172183

The two most notable ones being: Preventing enzymatic cleavage replacing Ala2 with -aminoisobutyric acid (Aib) to remove the DPP-4 cleavage site and avoid degradation

Our team strongly advises against pre-loading syringes for storage

Laboratories investigating vascular biology, wound healing models, and endothelial cell behaviour have incorporated this peptide into their research designs to examine how growth factor signalling influences vessel formation at the cellular level