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The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance-challenges and future research opportunities

The primary goal was to demonstrate that continuing with the drug meant sustained weight loss and health benefits

Semaglutide treatment over four months led to a weight reduction of 5 kg, from 118 kg (BMI 55 kg/m 2 ) to 113 kg (BMI 52.7 kg/m 2 )

Studies have demonstrated the efficacy of GLP-1RAs for glycemic control and their potential cardiovascular [41] and renal protective effects [42]

Endothelial cell behavior is regulated primarily through two metabolic pathways: glycolysis and fatty acid oxidation (FAO) [55, 56]