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Starting with a lower dose and gradually increasing it may help reduce adverse reactions

This suggests that treatment with arGLP-1 could be particularly beneficial for individuals struggling with suboptimal weight loss outcomes after surgery

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Once desired outcomes are achieved, treatment might shift to a lower maintenance dose or other supportive measures

Combination therapy with glucagon like peptide-1 receptor agonists has achieved synergistic effects, with weight loss exceeding 15%, positioning amylin analogs as a promising approach for treatment of diabesitythe co-existence of diabetes and obesity