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Its underlying mechanisms are multifaceted, encompassing genetic variations, environmental influences, cerebral artery constriction, abnormalities in monoamine neurotransmitters, oxidative stress, mitochondrial disturbances, the involvement of calcitonin gene-related peptide (CGRP), neurogenic inflammation, and broader neuroinflammation (6)

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Many of these compounds are traditionally limited in American-based diets

This integration traces the cascade of responses from molecular to phenotypic levels, providing a systems-level view of how plants adjust mineral nutrition to maintain homeostasis under stress