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The concept of targeting Wnt signals as a therapeutic approaches for alopecia stemmed from important role of Wnt/-catenin signaling in hair development and growth 3,4
Discussion With our approach combining epidemiological studies, explorative cellular experiments and murine interventions, we demonstrate that kidney function is the main modifiable factor consistently regulating fasting serum TMAO concentrations and that TMAO adversely impacts on eGFR, at least partially, by increasing kidney scarring synergistically with existing pathophysiology elevating kidney tissue TGF-1 signaling
Sergushichev, V
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