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As retatrutide is not yet licensed, women of childbearing potential participating in trials should follow the contraception and discontinuation guidance specified in their trial protocol

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Synthesis of Glutathione Glutamate-cysteine ligase converts glutamate and cysteine into gamma-glutamylcysteine, and glutathione synthetase adds glycine to form glutathione (GSH)

MC3R: Expressed in various tissues, including the brain and placenta, implicated in regulating appetite and energy homeostasis