glp-1 expression receptor expressing cells in the CNS. A, B. Demonstrates the Distinct Neural Sites of GLP-1R

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Although numerous studies have demonstrated that the amino-terminally truncated forms of GLP-1, GLP-1(7-37), and GLP-1(7-36) amide are active glucoregulatory hormones, no compelling bioactivities for the extended forms, GLP-1(1-37) and GLP-1(1-36) amide , have yet been determined