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Theoretical synthesis of the cytoprotective hypothesis

doi: 10.2217/pmt-2022-0063

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It contains a thiamine diphosphate cofactor and catalyzes thiamine diphosphate dependant decarboxylation of 2 oxoglutarate and subsequent reductive acylation of the oxidized lipoyl moiety LBD (lip-LBD-S2) which is covalently bound to the E2 component dihydrolipoamide succinyl transferase [5]

Potential Side Effects: While L-glutathione is generally regarded as safe, some individuals may experience side effects, including gastrointestinal discomfort