A 2015 meta-analysis in the Journal of Clinical Endocrinology & Metabolism found berberine reduced fasting glucose and improved HbA1c in patients with type 2 diabetes, with weight reductions averaging 23 kg over 12 weeks
Semaglutide supports weight loss efforts by acting similarly to a natural hormone called GLP-1, which is important for regulating blood sugar, slowing digestion, and controlling appetite
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I dont usually prescribe them together off the bat, but I do have patients come to me on metformin and will add a GLP-1 medication such as Wegovy, says Tzvi Doron, DO, DABFM, DABOM, a board-certified obesity and family medicine specialist in New York
This reduces the blood sugar spikes that can cause food craving, helping you to eat less