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SDSCs were isolated from human synovial tissues from five donors, ADSCs were purchased from Sigma-Aldrich, and UC-MSCs were isolated from human umbilical cords from five donors

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Meanwhile, MMP-9 amplifies the inflammatory cascade reaction by cutting and activating multiple pro-inflammatory factors and chemokines, promoting the recruitment and activation of inflammatory cells such as neutrophils into lung tissue, and causing tissue damage (Takahashi et al., 2018)

Ultimately, this process induces disseminated intravascular coagulation (DIC) in sepsis