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To prevent unauthorised sale, unsupervised use, and other malpractices, the Drug Controller of India has intensified its regulatory surveillance, warning that the drugs can lead to serious side effects if not taken under strict medical supervision

Myers SE, Whitman BY, Carrel AL, Moerchen V, Bekx MT, Allen DB

Gradual dose titration, as recommended in the Summary of Product Characteristics, helps minimise gastrointestinal disturbance

Over time, researchers discovered additional benefits beyond glucose management

Gastrointestinal adverse events were predominantly limited to initial dosing, while dose escalation resulted in lower discontinuation rates owing to these adverse events than among patients who remained on the starting dose