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Glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 are incretin hormones that regulate insulin secretion in response to nutrient intake, to facilitate glucose tolerance [81]

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Sources: - Lilly's next-gen drug tops Zepbound on weight loss in late-stage osteoarthritis trial (Published: 2025-12-11) - - American Association of Clinical Endocrinology Consensus Statement: Algorithm for the Evaluation and Treatment of Adults with Obesity/Adiposity-Based Chronic Disease - 2025 Update - PubMed (Published: 2025-01-01) - - Introduction and methodology: Standards of Care in Overweight and Obesity2025 | BMJ Open Diabetes Research & Care (Published: 2025-05-23) - #ObesityMedicine #WeightLoss #Retatrutide #TripleAgonist #GLP1 #ChronicDisease #HealthcareInnovation #Pharma #CardiovascularHealth #ObesityTreatment To view or add a comment, sign in Obesity, Metabolic Syndrome, and Osteoarthritis Require Integrative Understanding and Management by Mocanu, V., et al