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With aging, impairments in mitochondrial efficiency are associated with increased reactive oxygen species (ROS) production and declining bioenergetic capacity [10]

What to consider if your results are out of range: If you're low in folate, increase your intake of naturally folate-rich foods such as spinach and other dark greens, asparagus, Brussels sprouts, avocado, black-eyed peas and other legumes, and citrus fruits

PMID 26519340

Cons needles, refrigeration/storage, injection site care

That is effective in the short term, but it comes with trade-offs: increased infection risk, bone density loss, hormonal disruption