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Moreover, phospho-BCL-XL (Ser62) stabilizes G2 arrest by binding to and co-localizing with Cdk1 (cdc2) in nucleolar structures to avoid rapid nucleolar disassembly associated with mitosis onset, playing an unexpected role in the G2 phase checkpoint downstream of DNA damage distinct from its anti-apoptotic function 22

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IBS and GLP-1: What the Clinical Evidence Shows Recent data suggests that GLP-1 therapy does not worsen IBS in most patients when dosing is managed carefully