Urate Transporters and Genetics of Urate Transporter Pathologies A series of urate transporters including SLC and ABC transporters as well as several multispecific drug transporters (e.g., OAT1, OAT2, and ABCG2) maintain UA homeostasis (Figure 2) (Tomita et al., 2000
M.SerranoR.Benitez-BuelgaC.PopkesM.FormentiniI.et al (2016)
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3 Besides hyperglycemia, other risk factors that place patients at higher risk include hypertension, microvascular complications, such as diabetes-related nephropathy and neuropathy, dyslipidemia, and pregnancy