Furthermore, different studies employ varied sequencing methods (e.g., ITS1, ITS2, or 18S rRNA) and rely on fungal reference databases (e.g., UNITE, ITSoneDB) that are continuously updated 107,108 , which may introduce biases in species classification, lead to underdetection of low-abundance taxa, and complicate direct comparisons across studies
ROS, primarily generated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in activated immune cells, induce oxidative stress, lipid peroxidation, protein modification, and mitochondrial dysfunction, ultimately triggering apoptosis and compromising cellular function in metabolic and cardiovascular tissues (36, 37)
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Mutation of Glu170 decreased the reciprocal Dalziel coefficient 1/ 1 by up to 56% whereas 1/ 2 remained constant (Fig
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