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Patients who have struggled to lose weight through diet and exercise alone

doi: 10.3389/fnut.2023.1281879 Received 23 August 2023 Accepted 09 November 2023 Published 11 January 2024 Volume 10 - 2023 Edited by Maria Maisto, University of Naples Federico II, Italy Reviewed by Fortuna Iannuzzo, University of Naples Federico II, Italy

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Patients frequently report multi-week approval delays or outright denials based on plan language that excludes cosmetic or lifestyle-driven weight loss

Cleavage and deprotection: The peptide is cleaved from the resin and side-chain protecting groups are removed simultaneously using strong acid (typically trifluoroacetic acid with scavengers)