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While the MDL handles common issues like discovery, individual cases may eventually be sent back to their original courts for trial, where state-specific laws on damages, evidence, and negligence will apply

SELENOP maintains the activity of glutathione peroxidase 4 (Gpx4) by binding to LRP-1, preventing lipid peroxidation and ferroptosis, both of which contribute to neurodegeneration in AD [15]

These findings emphasize the need for individualized dose titration to identify the minimal effective dose per patient, maximizing therapeutic outcomes while minimizing side effects and reducing medication costs

Exp Mol Pathol (2019) 107:1248