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March 4, 2025 New NAION Study A recent study in JAMA Ophthalmology explored the potential link between semaglutide and non-arteritic anterior ischemic optic neuropathy (NAION), a rare eye condition that can cause sudden vision loss

and thus augmented the 3,5 cyclic adenosine monophosphate (cAMP) levels

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Indication: Polymorphic Photodermatosis Actinic Keratosis After organ transplantation or during immunosuppression treatments After photosensitising treatments (e.g., exfoliation / laser) Dermocosmetic procedures Prehistory of skin cancer Hyperpigmentation /Melasma Vitiligo Rosacea / Couperose and sensitive skin Coadyuvant in phototherapy Eye protection (given by Lutein) Cutaneous intolerance to sunlight Dermatologically, allergologically and ophthalmologically tested

HIF-1 forms a heterodimer with HIF-1 in the cytoplasm, translocates into the nucleus, and binds specific HREs on DNA, where it acts as a transcription factor for the downstream target gene VEGF ( Figure 3E )