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The preclinical safety information for Wegovy adds: In developmental toxicity studies in rabbits and cynomolgus monkeys, increased pregnancy loss and slightly increased incidence of foetal abnormalities were observed at clinically relevant exposures. While the company is now carrying out trials to explore whether such drugs are safe for pregnant women, at present it advises that semaglutide should not be used during pregnancy as it is not known if it may affect an unborn child

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The participants were randomly assigned to each active treatment group, semaglutide, liraglutide, or a corresponding placebo group using a block size of 56 in the studys randomized, double-blind, placebo-controlled design

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