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Nrgaard CH, Friedrich S, Hansen CT, et al

demonstrated that in SNCA A53T transgenic PD mice, exosomes from PD patients positive for L1CAM promoted the seeding of -syn and neuron loss [272]

Electrolyte shifts, especially low sodium or potassium after repeated vomiting or diarrhea, can also cause lightheadedness and should not be overlooked when a patient reports persistent symptoms

The loss of pigment in hair shafts because of decreased melanocyte function is typically known as graying, or going gray, although the exact cellular and molecular mechanisms are not yet completely understood

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