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Feng, S

In metabolic dysfunctionassociated steatohepatitis (MASH), for example, it remains uncertain whether improvements in hepatic inflammation and fibrosis are exclusively secondary to weight loss and metabolic improvements, or whether direct hepatoprotective mechanisms are involved

Cells were cultured at 37 C in a humidified atmosphere of 5% CO 2 with medium changed every 2 days until confluence

The prescribing information for tirzepatide specifically warns about oral contraceptives , advising patients who use oral birth control to consider a non-oral method or add a barrier method for four weeks after starting tirzepatide and after each dose increase