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Assays were carried out essentially as described in the literature 89,106 with the following specifics: TAMRA-atorvastatin ( 24 ) was used as the fluorescent tracer, and recombinant human PDE6 (Novus Biologicals, NBP1-44480) was used as the protein

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No amount of weight loss or specific clinical outcome can be guaranteed

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Cardiovascular Risk OSA significantly increases the risk of cardiovascular diseases, including hypertension, coronary artery disease, heart failure, and stroke [60]