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These digestive issues lead to skin issues like psoriasis and eczema

doi: 10.1038/s41586-019-1653-x, 34 EgeciogluE.EngelJ

These patients would include men 50 years of age or older and women 60 years of age or older with at least one other major risk factor including: hypertension, family history of CVD, smoking, dyslipidemia, or albuminuria

What sets it apart from Ipamorelin: Sermorelin was FDA-approved under the brand name Geref first as a diagnostic agent in 1990, then for GH deficiency in children in 1997 (Federal Register, PubMed)

Caloric deficit, adequate protein intake, resistance training to preserve lean mass