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doi: 10.1056/nejmoa2032183

Weight-loss injection maker buys Irish factory The maker of weight-loss drugs Ozempic and Wegovy has bought a factory in the Republic of Ireland as it seeks to increase production

The structural basis for this triple activity was elucidated through 2024 cryo-EM studies, which showed that retatrutides 26-amino acid backbone adopts distinct helical conformations at each receptor interface, explaining how balanced agonism across all three receptors is achievable without sacrificing binding affinity at any single target [9]

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Aging Cell 14(1):122129 Mangalmurti A, Lukens JR (2022) How neurons die in Alzheimers disease: implications for neuroinflammation