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Our study also provides mechanistic evidences on the role of adiponectin in G49 actions in weight loss by promoting hepatic FAO as reported 32

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While their main role remains in diabetes treatment, certain GLP-1 therapies are also approved for weight management in individuals with obesity or overweight with comorbidities, given their modest but clinically meaningful effects on appetite regulation and body weight 2 , 6 , 7

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