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Regul Pept 1999, 85: 924

In addition, compound YY-23 targets prefrontal cortical GABAergic interneuron NR2D-NMDARs, suppressing inhibitory GABAergic transmission while boosting excitatory signals to exert rapid antidepressant effects [43]

Thereby, BPC 157/NO relations (i.e., as both NOS-inhibition and NOS-over-activity could be harmful, and a modulating effect applicable in either circumstance should be needed to maintain the NO-system properly balanced and adequately functioning [124,125]) can appear as the essential neurotransmitter evidence

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