Does it increase blood pressure
As shown in Figure 3C, GSTP (Y7F) and GSTP (WT) equally restrained LPS-induced HMGB1 cytoplasmic translocation in RAW264.7 cells and NBDHEX (Figure 3D) also did not inhibit such effect of GSTP
*Correspondence: Yongye Huang, [email protected] This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation
Even more, ellagic acid has additionally been shown to increase monoamine oxidase B (MAO-B), nuclear factor (erythrocyte derivation 2), Nrf2, and heme oxygenase 1 (HO-1) and reduce the loss of tyrosine hydroxylase (TH)-positive neurons in the substantia nigra pars compacta (SNC) (Sarkaki et al., 2016)
