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Additionally, elevations in FFAs in obesity contributes to GH suppression, as experimental lowering of FFA levels reverses obesity-associated impairment of GH secretion (96)

Corticosteroid injections: Effective for pain relief but associated with collagen fiber weakening and increased re-injury risk with repeated administration

The simple application method is significant

Women with PMOS show chronically elevated pro-inflammatory cytokines particularly TNF-, IL-6, and CRP independent of obesity

More importantly, the combined formulation allows for lower individual doses while achieving superior overall healing effects through multi-pathway activation, making the therapy more convenient, cost-effective, and therapeutically powerful