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A Chinese oral drug at a fifth of that price undermines the entire margin structure on which the whole pipeline is builtand affects every investment case." Shah says, Revenue per patient drops 60 to 80 percent, and return on investment models built today at Rs2,000-plus collapse." He adds, however, that Rs500 to Rs800 pricing would require either a heavy market-capture subsidy strategy or a lower-efficacy molecule

Writers advise that the ASA guidelines should strongly emphasize the current absence of sufficient evidence

Long term (weeks 812): Consistency completely dominates timing

Trauner D (2023) Neuro-cognitive complications of nephropathic cystinosis

doi: 10.1016/j.jad.2020.01.050