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Generation of cellular ROS production, decrease in nitric oxide bioavailability, and activation of enzymes like NADPH oxidase, and many signaling factors induce oxidative stress followed by breakdown of redox balance with consequential development of physiological and metabolic disorders, including endothelial dysfunction, inflammation and increasing concentration of VSMCs

doi: 10.1111/apt.18006 182 YuF.HuX.RenH.WangX.ShiR.GuoJ.et al

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It is more powerful than Vitamin C, more critical than Vitamin E, and it is working inside every single cell you have right now