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These types of studies are the gold standard of scientific research in humans

Nrf2 activators as dietary phytochemicals against oxidative stress, inflammation, and mitochondrial dysfunction in autism spectrum disorders: a systematic review

On the other hand, in case of excessive distress, cells are exposed to high levels of ROS which can cause neuroinflammation, damage to the blood-brain barrier (BBB) and impairment to astrocyte crosstalk leading to ASD (Russo et al., 2018)

Key randomized controlled trials have demonstrated its efficacy in improving histologic measures of hepatic inflammation and fibrosis

Single-cell profiling reveals age-associated immunity in atherosclerosis