It is involved in producing red blood cells, the functioning of the nervous system, and the metabolism of cells throughout the body
It exerts a critical physiological effect in the excretion of UA in the kidney and intestine (Maliepaard et al., 2001
In assessing the complex interconnection of gut metabolites with renal and cerebrovascular endothelial dysfunction, proximal tubule dysfunction, and podocyte injury, a study found that metabolites belonging to the retinoic acid signaling and nitrogen metabolic pathways could differentiate normoalbuminuria (P1) from microalbuminuria (P2) and macroalbuminuria (P3) patients
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