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Most Common Side Effects Dry mouth Insomnia or disrupted sleep Increased heart rate or blood pressure Mild nausea (typically dose-related and temporary) Restlessness or mild anxiety in sensitive individuals Adverse events were mostly mild to moderate and occurred during early weeks of treatment

Additionally, those who follow a vegan lifestyle are typically deficient as they do not get nearly enough B12 without having animal products as a part of their diet

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"Prevalence of vitamin B12 deficiency in type 2 diabetic patients using metformin: a cross-sectional study"