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SIRT1 Activation: Promotes fat oxidation, muscle preservation, and reduced inflammation (Price et al., Cell Metabolism )

Other counterions should not be assumed equivalent without evidence

Yes, Methylcobalamin is a safe and well-tolerated form of B12, prescribed by licensed professionals and commonly used for energy support and B12 deficiencies

The bigger thing to watch is your total caffeine intake and whether it's cutting into your sleep, since poor sleep will undermine any micronutrient strategy

In practice a GP or nurse may administer off-licence by giving a sub-cutaneous (under the skin, SC) injection but it is important to remember that the GP makes their own decision and takes their own accountability and reliability if they go off-licence