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Moreover, Ogt deficiency in NSCs resulted in a range of severe brain developmental impairments, such as decrease in cell proliferation, inhibition of neuronal dendritic and axonal differentiation, shrinkage of cortex and hippocampus, and apoptosis of neurons [30]

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74%81% in the other trials), a greater mean age (55 years vs

methionine synthase, MCM: methylmalonyl-CoA mutase

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