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10.1016/j.bbrc.2017.12.112 11 ChenC.LiuX.LiL.GuoM.HeY.DongY.et al (2024)

The Key Difference: Dual vs Triple Agonism The fundamental distinction between these compounds lies in how many receptors they target: This additional glucagon receptor activation in retatrutide represents a significant mechanistic difference that researchers believe may contribute to its observed effects in clinical studies

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