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In RBL-2H3 cells, Aceriphyllum rossii (ARE), a substance rich in quercetin and kaempferol, inhibited the histamine release by about 40% and PGE 2 release almost completely [51]

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Similarly, acetaminophen overdose leads to the formation of a toxic metabolite, N-acetyl-p-benzoquinone imine (NAPQI), which depletes glutathione and induces oxidative stress in the liver [57]

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Department of Primary Industries and Regional Development