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2A, B, and Dataset S1) to investigate the underlying mechanism

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Research findings: A 2003 study by Khavinson et al

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Genetic changes: Certain inherited traits may make melanocytes more fragile or prone to immune attack, increasing the risk of vitiligo

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Furthermore, SOD1 undergoes the cyclic reduction and oxidation of copper ions (Mccord and Fridovich, 1969), and it also inhibits oxidative inactivation of nitric oxide to prevent peroxynitrite formation (Harraz et al., 2008)

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Little inflammatory cell infiltration was evident in the lamina propria and no edema was observed (Fig

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